Friday, February 19, 2010

Urushiol - science fact of the day

So, in researching poison oak (because, now that I'm a scientist, I should be able to comprehend complex mechanisms of allergic reactions blablabla), I learned that the oily toxin, urushiol, found in poison oak, poison ivy, and poison sumac (or maybe it's just called sumac), is a catechol - a benzene ring with two neighboring alcohol functional groups - with an alkyl substituted side chain... in this case, the alkyl is a long hydrocarbon side chain, either saturated or unsaturated (which gives the compound its oily nature). The urushiol oil is actually a mixture of these catechol substituted groups, with varying proportions of the saturated and unsaturated side chains (and different degrees of unsaturation). Interestingly, people are more sensitive to the unsaturated versions, and lo! Poison oak has lots of unsaturated side chains. Who'da thunk?
When the oil/ toxin touches a skin cell, it binds to proteins on the cell surface, and changes their conformation. THEN (now this is the craazzyy part) - our immune system doesn't recognize our own cells any longer (because the surface proteins are different), so our immune system attacks the cells in an allergic response.


ok, now that that's over, let me just say that I despise people who don't do their homework and then try to weasel out of responsibility for their laziness. In my keyboard class (ok, so I realize that it's a lower division keyboard requirement for most music majors, so "who cares"), NOBODY practices... or if they do, it must be like ten minutes tops. We had our second midterm today, and half the class didn't even show up until there were only 15 minutes left in the class - hoping there would not be enough time on that day for them to go - and others begged to go last, or next-to-last. I, and a few other pseudo-prepared students offered to go, if only because we were then allowed to leave upon completing the midterm...
A few weeks ago, during the previous midterm, one girl (who had obviously not prepared at ALL), asked if she could go on the following monday. Teacher said no (thank goodness). Then she couldn't play any of the scales, any of the pieces, or any of the finger excercises. NOTHING. By the end of her miderm, she was tearful and resentful, and the teacher was furious. Not directly at her, but at being put in such an uncomfortable position. nobody likes to make girls cry, least of all a sweet mormon pianist, and after she left (tears streaming after her), he ranted at the rest of the class... i guess it felt like he was preaching to the choir, but I'm sure there were some dissidents in the class....
why can't people just take care of their business.
GEEZ

ok, that's all for now
oh, and the poison oak welts on my face were oozing fluid all day. gross.

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